Key Laboratory of Ecological Adaptive Evolution and Conservation on Animals-Plants in Southwest Mountain Ecosystem of Yunnan Province Higher Institutes College, School of Life Science of Yunnan Normal University, Kunming; 650500, China;

Yunnan Normal University, Engineering Research Center of Sustinable Development and Utilization of Biomass Energy Ministry of Education, Kunming 650500;

Key Laboratory of Yunnan Province for Biomass Energy and Environment Biotechnology, Kunming 650500

Acetylcholinesterase (AChE) is a ubiquitous, stable and easily verified enzyme in the central nervous system of mammals. Superoxide dismutase (SOD) is one of the most effective antioxidants known in organism, which is an important part of cell to resist oxidative stress. Many studies have expounded that AChE affected spatial memory impairment in mammals, and SOD had effects on extracellular overexpression and antioxidant stress. In the present review, the structures and measurement methods of AChE and SOD were introduced, and the mechanism of improving the memory ability of animals by regulating the cell resistance to oxidative stress in the organism were also introduced. The effects of AChE and SOD on memory ability in different species were analyzed, suggesting the application prospect of AChE and SOD in treating the symptoms of human Alzheimer's disease (AD).

Keywords: Memory ability; assays; oxidative stress; Alzheimer’s disease