Pure silver nanoparticles showed potential anticancer effect on colon and breast cancer cell lines

  • strict warning: Non-static method view::load() should not be called statically in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/views.module on line 1113.
  • strict warning: Declaration of views_handler_argument::options_validate() should be compatible with views_handler::options_validate($form, &$form_state) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/handlers/views_handler_argument.inc on line 0.
  • strict warning: Declaration of views_handler_argument::query() should be compatible with views_handler::query($group_by = false) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/handlers/views_handler_argument.inc on line 0.
  • strict warning: Declaration of views_plugin_pager_none::post_execute() should be compatible with views_plugin_pager::post_execute(&$result) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/plugins/views_plugin_pager_none.inc on line 0.
  • strict warning: Declaration of views_plugin_query::options_submit() should be compatible with views_plugin::options_submit($form, &$form_state) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/plugins/views_plugin_query.inc on line 0.
  • strict warning: Declaration of views_plugin_argument_default_taxonomy_tid::options_submit() should be compatible with views_plugin_argument_default::options_submit($form, &$form_state) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/modules/taxonomy/views_plugin_argument_default_taxonomy_tid.inc on line 0.
  • strict warning: Declaration of views_plugin_style_default::options() should be compatible with views_object::options() in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/plugins/views_plugin_style_default.inc on line 0.
  • strict warning: Declaration of views_plugin_row::options_validate() should be compatible with views_plugin::options_validate(&$form, &$form_state) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/plugins/views_plugin_row.inc on line 0.
  • strict warning: Non-static method view::load() should not be called statically in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/views.module on line 1113.
  • strict warning: Non-static method view::load() should not be called statically in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/views.module on line 1113.
  • strict warning: Non-static method view::load() should not be called statically in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/views.module on line 1113.
  • strict warning: Declaration of views_handler_field::query() should be compatible with views_handler::query($group_by = false) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/handlers/views_handler_field.inc on line 0.
  • strict warning: Declaration of content_handler_field::element_type() should be compatible with views_handler_field::element_type($none_supported = false, $default_empty = false, $inline = false) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/cck/includes/views/handlers/content_handler_field.inc on line 0.
  • strict warning: Declaration of views_handler_filter::options_validate() should be compatible with views_handler::options_validate($form, &$form_state) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/handlers/views_handler_filter.inc on line 0.
  • strict warning: Declaration of views_handler_filter::query() should be compatible with views_handler::query($group_by = false) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/handlers/views_handler_filter.inc on line 0.
  • strict warning: Declaration of views_handler_filter_search::exposed_validate() should be compatible with views_handler::exposed_validate(&$form, &$form_state) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/modules/search/views_handler_filter_search.inc on line 0.
  • strict warning: Declaration of views_handler_area::query() should be compatible with views_handler::query($group_by = false) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/handlers/views_handler_area.inc on line 0.
  • strict warning: Declaration of views_handler_area_text::options_submit() should be compatible with views_handler::options_submit($form, &$form_state) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/handlers/views_handler_area_text.inc on line 0.
  • strict warning: Non-static method view::load() should not be called statically in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/views.module on line 1113.
  • strict warning: Declaration of views_handler_sort::options_validate() should be compatible with views_handler::options_validate($form, &$form_state) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/handlers/views_handler_sort.inc on line 0.
  • strict warning: Declaration of views_handler_sort::options_submit() should be compatible with views_handler::options_submit($form, &$form_state) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/handlers/views_handler_sort.inc on line 0.
  • strict warning: Declaration of views_handler_sort::query() should be compatible with views_handler::query($group_by = false) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/handlers/views_handler_sort.inc on line 0.
  • strict warning: Non-static method view::load() should not be called statically in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/views.module on line 1113.
Mohd Salim Reshi, Gaurav Bhatia, Deepa Yadav, Chhavi Uthra, Sadhana Shrivastava Jatinder Singh Arora and Sangeeta Shukla

UNESCO- Trace Element Satellite Center School of Studies in Zoology, Jiwaji University, Gwalior (M.P). India

Protein Lab, Department of Biochemistry and Molecular Biology, Guru Nanak Dev University, Amritsar

 

Present study was designed to investigate the anticancer potential of silver nanoparticles (AgNPs) on Human cancer cell lines (MCF-7 & HCT-15). AgNPs showed a dose-dependent toxicity towards both the cell lines. AgNPs decreased the viability of tested cells to 50% at 24.44ppm for MCF-7& 12.89ppm for HCT-15 cells respectively. Percent cytotoxicity of AgNPs was determined by Lactate dehydrogenase (LDH) Assay. LDH activities in medium of AgNPs treated cells were found to be significantly elevated on both the cell lines as compared to the non treated cells. This study revealed that AgNPs demonstrate strong anticancer potential on MCF-7 and HCT-15, however more effect was observed on MCF-7 than HCT-15 cell.

 

 

Key words: Silver nanoparticles,MCF-7, HCT-15, Anticancer

application/pdf icon| PDF (861 KB) |