Department of Chemistry, Uttaranchal University, Dehradun-248001, India

In this paper different types of physical and chemical methods are listed with their disadvantages. The mission is to review these methods properly and to understand why these methods are losing their presence day by day. Green synthesis method and biosynthesis has been discussed with their advantages and enhanced applications. The applications of titanium dioxide nanoparticles, their different biomedical applications are listed. Therefore this paper used various sources to collect the review articles. Green synthesis was found to be a cost effective and ecofriendly method as compared to different bottom up and top down methods. Different plant extracts are used to synthesize titanium dioxide nanoparticles which are listed in this paper. Titanium dioxide nanoparticles can be used as effective metal oxide nanoparticles for different biomedical applications and also as a smart substitute for catalytic reactions.