To study the biofilm formation and antibacterial activity of some medicinal plants against Streptococcus sp. isolated from diabetes type 2 patients

  • strict warning: Non-static method view::load() should not be called statically in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/views.module on line 1113.
  • strict warning: Declaration of views_handler_field::query() should be compatible with views_handler::query($group_by = false) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/handlers/views_handler_field.inc on line 1147.
  • strict warning: Declaration of content_handler_field::element_type() should be compatible with views_handler_field::element_type($none_supported = false, $default_empty = false, $inline = false) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/cck/includes/views/handlers/content_handler_field.inc on line 229.
  • strict warning: Declaration of views_handler_filter::options_validate() should be compatible with views_handler::options_validate($form, &$form_state) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/handlers/views_handler_filter.inc on line 587.
  • strict warning: Declaration of views_handler_filter::query() should be compatible with views_handler::query($group_by = false) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/handlers/views_handler_filter.inc on line 587.
  • strict warning: Declaration of views_handler_filter_search::exposed_validate() should be compatible with views_handler::exposed_validate(&$form, &$form_state) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/modules/search/views_handler_filter_search.inc on line 112.
  • strict warning: Declaration of views_handler_area::query() should be compatible with views_handler::query($group_by = false) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/handlers/views_handler_area.inc on line 81.
  • strict warning: Declaration of views_handler_area_text::options_submit() should be compatible with views_handler::options_submit($form, &$form_state) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/handlers/views_handler_area_text.inc on line 121.
  • strict warning: Non-static method view::load() should not be called statically in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/views.module on line 1113.
  • strict warning: Declaration of views_handler_sort::options_validate() should be compatible with views_handler::options_validate($form, &$form_state) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/handlers/views_handler_sort.inc on line 165.
  • strict warning: Declaration of views_handler_sort::options_submit() should be compatible with views_handler::options_submit($form, &$form_state) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/handlers/views_handler_sort.inc on line 165.
  • strict warning: Declaration of views_handler_sort::query() should be compatible with views_handler::query($group_by = false) in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/handlers/views_handler_sort.inc on line 165.
  • strict warning: Non-static method view::load() should not be called statically in /home/u809185268/domains/sciencebeingjournal.com/public_html/sites/all/modules/views/views.module on line 1113.
Manisha Nanda, Vinod Kumar, Rajendra Prasad and Saurabh Pant

Dept. of Biotechnology, Dolphin (PG) Institute of Biomedical and Natural Sciences, Dehradun, Uttarakhand, India

Dept. of Chemistry, Uttaranchal University, Dehradun, Uttarakhand, India

Dept. of Forestry, Uttaranchal University, Dehradun, Uttarakhand, India

Type 2 diabetes patients have significantly higher plaque index and a higher prevalence and magnitude of root surface caries than non-diabetic subjects. In the present study we have isolated two Streptococcus sp. from oral samples of diabetes type 2 patients and studied the biofilm formation by these bacteria. Biofilm formation act as a defensive method during various stress conditions for some bacteria. Streptococcus mutans, the principle cariogen for dental caries, co- exist with over 500 other species of bacteria as an interactive community known as the dental biofilm (Jubai 2015). The inhibitory effect of some medicinal plants against the isolated Streptococcus sp. were also studied.  For this purpose Walnut (Juglans regia) stem bark, cinnamon (Cinnamomum zeylanicum) and clove (Syzygium aromaticum) extracts were used. The results obtained displayed that the aqueous extract of clove exhibits highest antibacterial activity against these isolated biofilm forming Streptococcus sp. C1 and Streptococcus sp. C2.

 Key words: Biofilm;antibacterial activity; diabetes type 2; Streptococcus sp.; Plant extract.

application/pdf icon| PDF (879 KB) |