Synthesis, Characterization and Chelating Properties of Pyrimidine-Quinoline Combined Molecule with Transition Metals

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Purvesh J. Shah

     Department of Chemistry, Shree P. M. Patel Institute of P. G. Studies and Research in Science, Anand, Gujarat (INDIA)

Thetreatment of ethyl-6-methyl-2-oxo-4-phenyl-1,2-dihydropyrimidone-5-carboxylate with 5-amino-8-hydroxyquinoline afford a N-(4-hydroxyquinolin-5-yl)-6-methyl-2-oxo-4-phenyl-1,2-dihydro pyrimidine-5-carboxamide(PDHQ). The transition metal complexes of Cu2+,Co2+ ,Ni2+, Mn2+ and Zn2+ of PDHQ have been prepared and characterized by elemental analysis, spectral studies, magnetic moment determination, molar conductivity measurement and microbicidal activity.

Keywords: Ethyl-6-methyl-2-oxo-4-phenyl-1,2-dihydropyrimidone -5-carboxylate, 5-amino-8-hydroxyquinoline, Antimicrobial activity, Magnetic moment, Metal chelates

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